About Cycle for Survival

Cycle for Survival is the high-energy indoor team cycling event
that provides a tangible way to beat rare cancers.
Read more
about the national movement and join the battle today!

The Cause

Our Cause
More than half of people diagnosed with cancer have a rare form of the disease.

According to the National Institutes of Health (NIH), a "rare cancer" is one with a prevalence of fewer than 200,000 affected individuals in the United States. Research on many rare cancers is drastically underfunded, leaving patients with limited treatment options. Memorial Sloan Kettering Cancer Center, the nation's preeminent center for cancer research and treatment, is committed to changing that.

Quick Facts:
50% of people with cancer are battling a rare cancer.
Rare cancers include brain, pancreatic, thyroid, and stomach cancers; leukemia and lymphoma; all pediatric cancers; and many others.
Each year MSKCC treats more than 400 subtypes of cancer.

100% Goes to Win the Battle

Our Movement
Cycle for Survival's indoor team cycling event raises funds for rare cancer research.

100% of the funds go directly to Memorial Sloan Kettering Cancer Center and are allocated within six months of each event. The donations go to the most promising research and clinical trials, and have led to better treatments for cancer patients worldwide. If you want to actively fight cancer, join the battle with us.

Take action against rare cancers.

Quick Facts:
Jennifer Goodman Linn and her husband, Dave, founded Cycle for Survival in 2007.
100% of the funds go directly to Memorial Sloan Kettering Cancer Center.

Direct Impact

Direct Impact

Since its inception in 2007, Cycle for Survival has raised over $51.5 million for rare cancer research and contributed to 85 clinical trials and research studies. The direct funding has drastically reduced the time it takes for treatments to reach patients—in some cases cutting the span from years to months.

Doctors and researchers who've received Cycle for Survival funding credit these resources for making groundbreaking discoveries possible, advancing vital research where—sometimes—little to no funding exists.

Quick Facts:
Since 2007, Cycle for Survival has raised over
$51.5 million .
Cycle for Survival has directly contributed to 85 clinical trials and research studies.

Cycle for Survival will fund these projects in 2012:

Research in the Cancer Biology and Genetics Program

Cancer Biology and Genetics Program scientists are working to determine whether inhibiting a gene called CSF-1R might suppress the development of certain brain tumors called gliomas.

Study of Residual and Recurrent Glioma

Investigators in the Cancer Biology and Genetics Program are studying residual and recurrent glioma to learn more about how brain tumor cells manage to resist conventional therapies.

Comprehensive Molecular Profiling of Ovarian Cancer

Physicians in the Gynecologic Medical Oncology Service are employing comprehensive molecular profiling of low-grade serous and serous borderline ovarian cancer.

New Therapies on Pancreatic Neuroendocrine Tumors

Radiologists are working to develop innovative ways to measure the effects of new therapies on pancreatic neuroendocrine tumors

The Role of New Drug, PD0331991

Scientists in the Molecular Biology Program are exploring the role of a promising new drug, called PDO331991, in the treatment of glioma.

Physicians in the Lymphoma Service are studying innovative new therapies for T-cell lymphomas.

Study Within the Sarcoma Consortium

A study conducted within the sarcoma consortium (a collaboration of 20 clinical centers) has shown that a novel combination of two drugs controls tumor growth better than either drug administered alone. And based on preclinical data made possible by Cycle funds, MSKCC has been approved to begin the first clinical trial to test a drug that inhibits a protein called Aurora Kinase A. The study will have the support of the NCI and will be brought directly into the sarcoma consortium.

Phase II Study of Drug, MK-2206

Physicians in the Head and Neck Medical Oncology Service are conducting a Phase II study of a drug, called MK-2206, in patients with a progressive recurrent/metastatic adenoid cystic carcinoma, a rare cancer that often occurs in the head and neck. .

Genome Sequencing to Study Urothelial Neoplasm

Physicians in the Department of Pathology are using whole genome sequencing a process that determines the complete DNA sequence of an organism’s genome at a single time to study a rare but aggressive cancer called urothelial neoplasm.

Download more information

Rare Cancer Fact Sheet

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Cycle for Survival Funded Research

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